In-person Flagship Gathering 2027

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Transform

Save the Date:
2027 Flagship Event

10–11 May 2027

PRBB, Barcelona, Spain

Flagship Event

The Global Think-tank on Steatotic Liver Disease will return to Barcelona on Monday 10 and Tuesday 11 May 2027, bringing together leading voices from research, clinical practice, public health, policy and lived experience to advance action on steatotic liver disease (SLD).

Building on the momentum of our 2026 Flagship Event and International Media Workshop, the 2027 meeting will turn attention towards what comes next: translating global commitments into meaningful implementation.

Discover 2026 Flagship Event

About the event

With the adoption of the World Health Assembly resolution on SLD, the challenge now is to support countries and health systems in moving from commitment to action and monitoring. The 2027 Flagship will contribute to this next phase, with a particular focus on the:

SLD resolution
action plan

Indicators for
monitoring progress

Practical changes across
the continuum of care

Sessions will explore how SLD, including MASLD, MASH and MetALD, can be more effectively integrated into metabolic health, NCD strategies and health systems worldwide.

Programme at a glance

Monday 10 May
08:00–13:00 | International Media Workshop (by invitation only)
13:00–19:00 | Flagship Programme
19:00–21:00 | Evening Reception

Tuesday 11 May
09:00–16:00 | Flagship Programme

An intentionally different kind of meeting

Attendance is limited to approximately 120 participants, maintaining the Think-tank as an intimate and highly interactive space for exchange, collaboration and problem-solving.

Save the date. More information on the programme and participation will follow.

Hear More from Last Year’s Event

Where does the conversation need to go next [PT-BR]

Cynthia Valerio

Endocrinologista e presidente eleita da ABESO — Associação Brasileira para o Estudo da Obesidade e da Síndrome Metabólica

What does #AmplifyTheConversation mean from where you stand?

Ferdinant M. Sonyuy

Executive Director of the Africa NCDs Network

What question should senior leaders be asking more often?

Melina Manolas

MD, MPH, Endocrinologist and Assistant Professor of Clinical Medicine at Weill Cornell Medicine

See More from Last Year’s Event

Opening Remarks & Keynote Addresses

Diagnostic Innovations and Models of Care for Steatotic Liver Disease

This session examined gaps in the continuum of care for steatotic liver disease and explored how novel technologies, including non-invasive and point-of-care screening/case-finding tools, and integrated care models could improve early detection, access, and long-term management. It highlighted multidisciplinary and community-based approaches and assessed barriers related to the adoption of new technologies, digital literacy, and the social determinants of health.

Policy Readiness to Confront the Steatotic Liver Disease Public Health Threat

This session explored opportunities for health systems and policy reform to integrate liver care into broader non-communicable disease strategies and research priorities to support more equitable and sustainable care. The session assessed policy readiness to arrest the rising tide of steatotic liver disease and to meet the increasing demand for treatment and care, including in national policies, clinical guidelines, and strategic frameworks. It further addressed the inclusion of SLD in liver-specific, healthy lifestyle, and NCD policies, as well as policies on key comorbid conditions such as diabetes, obesity, and cardiovascular disease.

Where MetALD and ARLD Meet in Metabolic Care

In this session, we examined the social and economic roots, stigma, and implications for the prevention and treatment of MetALD and ARLD. We further investigated systemic issues such as under-screening, knowledge gaps, and the limited use of non-invasive diagnostic tools, including PEth (phosphatidylethanol), EtG (ethyl glucuronide), EtS (ethyl sulfate), and AUDIT-C (Alcohol Use Disorders Identification Test-Concise).

Closing Keynotes

…or explore our media appearances

In the Media

The Venue

Situated in one of Barcelona’s most dynamic innovation hubs, the Barcelona Biomedical Research Park (PRBB) provides an inspiring environment for hosting events. The building brings together leading research institutions and professionals from around the world, fostering collaboration and knowledge exchange.

Its modern architecture and open design reflect the spirit of scientific discovery that defines the venue. Each year, around 300 scientific sessions and conferences are held within the research park.

Carrer del Doctor Aiguader, 88 ES – 08003 Barcelona
Visit venue website

Become a sponsor

Interested in becoming a sponsor of the event?

Showcase your business to a diverse audience, including hepatologists, endocrinologists, primary care physicians, researchers, the patient community, and representatives from the private sector.

As a sponsor, you’ll get unique visibility through strategic logo placements, exhibition space, social media exposure, networking opportunities, and more. Contact our sponsorship team to find out more about the various sponsorship packages available.

Contact sponsorship team

Additional inquiries

Would you like to collaborate or partner with us? Do you have any questions?

Feel free to reach out!

admin2026-10-01T15:30:39+00:00

Registration fees

All applications for registration will be reviewed, and you will be notified of your invitation status and fee via email within one week.

Category	Early Bird (before 1 April)	After / onsite
Private Sector/Industry	295	350
Start-up*	95	150
Healthcare Professional, Academic, Public Health/Professional Association, NGO	75	100
Young Researcher / Trainee / PostDoc / Student / Young Person (under 25) *	45	60
Patient with lived experience *	free	free
Patient or Patient Representative *	45	50

* Registration fee scholarship offered on application, please email: lisa.rice@isglobal.org

Criteria for start-ups:

Early-stage startup (e.g., pre-seed, seed, or Series A).
Incorporated for under 5 years
Raised under $5 million in funding
Annual revenue less than $1 million
Fewer than 50 employees

What’s included in your ticket?

Entry to lunch main agenda sessions 1pm-7pm on 26 May and evening reception

5. Strengthen the capacity of community health services to prevent and treat MASLD through social prescribing

Primary care has a well-established network of health centres across Spain. In the last years, there has been an increase in the number of community-based activities promoting well-being and reducing the metabolic risk profile through social prescribing. These activities usually integrate exercise through increasing physical activity.⁴⁵ Strengthened primary care systems can reinforce the role of community health services by incorporating social prescribing models to address lifestyle drivers of MASLD in vulnerable populations, such as physical activity, which is a recommended first-line therapy of people with MASLD, and can improve psychosocial health,⁴⁶ which is often reported as poor by people living with MASLD.⁴⁶ By facilitating participation in community-based activities like group exercise, arts, or wellness programs, social prescribing addresses both physical inactivity and the isolation or low mood commonly seen in this population.⁴⁷ In Catalonia, the Programa de Prescripció Social i Salut exemplifies this approach by linking patients to local community assets via an integrated system in primary care, particularly targeting conditions such as anxiety, depression, and social isolation,⁴⁴ and which may be beneficial for people living with MASLD/MASH. Elsewhere, social prescribing has demonstrated benefit for people living with diabetes.⁴⁸ Evaluation data from Catalonia show that over 70% of participants report improvements in emotional well-being and social support after engaging in prescribed community activities frequently related to physical activity.⁴⁴

5. Leverage electronic health records (EHR) through integrated automated diagnostic tools

Integrating MASLD/MASH screening algorithms into existing EHR systems can substantially enhance early detection and risk stratification in primary and secondary care. Automated tools such as intelligent liver function testing (iLFT)—which systematically interprets routine liver function tests, performs reflex testing, and identifies likely liver diseases for physicians to consider—have shown promise in improving early diagnosis and care pathways, particularly in underdiagnosed conditions like MASLD and MASH.⁴³ In the Spanish context, where nearly 10 million individuals may be living with MASLD by 2030,³ embedding such tools in the primary care EHR systems used across autonomous communities could standardise assessment, reduce diagnostic delays, and promote timely secondary referrals. Moreover, this approach complements digital transformation priorities already outlined in Spain’s National Health System and aligns with the objectives of the Strategic Framework for Primary and Community Care (2019).^26,44

4. Increase awareness and education of MASLD/MASH among at-risk groups and healthcare professionals

Enhancing awareness of MASLD/MASH among both at-risk populations—such as those living with obesity, diabetes, and metabolic syndrome—and frontline healthcare workers is critical for early identification, appropriate risk stratification and timely intervention. Given its silent clinical course, MASLD is often underdiagnosed until advanced stages, particularly in primary care settings where patients with obesity, diabetes, or metabolic syndrome are commonly managed.

Spain’s Strategic Framework for Primary and Community Care (2019) already emphasises chronic disease prevention, making it an ideal entry point for MASLD/MASH education.²⁶ Yet, existing knowledge gaps among primary care providers regarding liver disease etiology, progression, and appropriate screening necessitate awareness or education campaigns and professional training modules that build the knowledge and clinical skills needed to manage MASLD in frontline settings.^24,41 A cohesive and comprehensive educational strategy is essential and could begin with the integration of MASLD/MASH-specific content into undergraduate, specialty, and continuing medical education curricula to foster competency in metabolic hepatology across the care continuum. A national interdisciplinary training strategy could bring together professionals from family medicine, endocrinology, cardiology, nephrology, internal medicine, endoscopy, clinical nutrition, and hepatology to address MASLD/MASH as a complex, multisystemic disorder.

A comprehensive communication and engagement health literacy strategy should position MASLD/MASH as serious, progressive, and multisystemic conditions. This involves dismantling the minimising narrative of “fatty liver” and clearly linking MASLD to major outcomes such as cardiovascular, renal and metabolic disease. Such a campaign should incorporate the concept of MetALD, which captures the under-recognised harm of moderate alcohol use in people with MASLD. Establishing a national MASLD/MASH patient platform would also enable the co-design of care pathways, educational materials, public campaigns, and research priorities, ensuring patient-centered policy and practice.

Finally, it is critical to explicitly position MASLD within the cardio-renal-metabolic axis, evolving toward a CHRM model (cardiovascular-hepatic-renal-metabolic).⁴² This paradigm recognises the liver as a pivotal organ in systemic metabolic dysfunction. The CHRM paradigm reflects the shared pathophysiology and clinical trajectories of MASLD, T2DM, chronic kidney disease, and cardiovascular disease. Scientific societies and patient organisations in Spain must collectively support and disseminate this integrative model, aligning MASLD policy with broader strategies for non-communicable diseases.

3. Add MASLD/MASH as an indicator to the list of Key Health System Indicators

Despite the rising clinical, social, and economic burden of MASLD, this condition is not currently included among Spain’s Key Health System Indicators, which guide monitoring, evaluation, and resource distribution across the National Health System.14 Integrating MASLD/MASH as a formal indicator would recognise the disease as a strategic health priority by integrating it into the national health information system, guiding decision-making on screening, diagnosis, and care pathways. Failure to track this disease risks underestimating its long-term economic and public health impacts. Incorporation into the indicator framework aligns with Spain’s commitment to data-driven governance and would support benchmarking across autonomous communities. To support targeted local action on MASLD, tools at the autonomous community level should be developed to guide policy and programme implementation. A MASLD risk index, combining aggregated clinical data, social determinants of health, and population-level metrics, can help identify high-need areas and inform municipal-level screening strategies. In parallel, a MASLD Impact Score should be created to assess the effectiveness of local policies related to metabolic health, food regulation, healthy environments, early detection practices, and workforce training. This metric could be implemented through municipal initiatives such as the upcoming “Santander se mueve” health promotion program, set to launch in September 2025.

2. Create a national MASLD registry, cohort, or observatory

Establishing a national MASLD registry, cohort or observatory is a critical step toward advancing clinical management, research, and policy evaluation. A national registry would enable the systematic collection of epidemiological, clinical, and sociodemographic data, essential for monitoring disease prevalence and progression, identifying high-risk subgroups, and assessing territorial disparities in access to care. While the Epidemiological sTudy of Hepatic infectiONs (ETHON) cohort estimated that 1.33%% of the Spanish population from 2015-2020 had MASH with fibrosis (stage F2-F3), these findings are limited to participants from primary care centers in Madrid, Santander and Valencia.^12,39 Additionally, while national clinical registries like HEPAmet and REGHNA (focused on hospital settings) provide important data, they are not population-based, nor are they consistently linked with public health surveillance systems.⁴⁰ A standardised and centralised MASLD registry would enable longitudinal tracking of this more prevalent disease, facilitate research on progression and treatment outcomes, and help evaluate the impact of interventions over time. Furthermore, registry data could support regional health planning and inform clinical practice guidelines aligned with Spain’s digital health transformation efforts.

1. Launch a Ministry of Health-led whole-of-government strategy

The growing prevalence of MASLD and MASH in Spain—projected to affect over 27% and 5.9% of the population, respectively, by 2030—necessitates an integrated, cross-sectoral policy response,³ led by an intersectoral working group under the leadership of the Ministry of Health. This whole-of-government initiative could facilitate the mainstreaming of MASLD/MASH into key national strategies addressing chronic diseases in general, and obesity, diabetes, and cardiovascular health specifically through a “health in all policies” approach. These strategies include the Strategy for Addressing Chronic Diseases (2012),²⁷ the Diabetes Strategy (2006)²⁸ and its 2012 update²⁹, and the Cardiovascular Health Strategy (2022),³⁰ where MASLD/MASH remain largely underrepresented despite their metabolic underpinnings. This omission contributes to fragmented care and missed opportunities for early intervention. Systematic integration of MASLD across these strategies would allow Spain to align with recommendations from the EASL–Lancet Liver Commission, which urges countries to address liver diseases through upstream, equity-based, and multisectoral policies.³²

Crucially, national leadership must be paired with urban action. Cities are where obesogenic environments, food insecurity, and social inequalities converge with high diabetes and obesity prevalence. An initiative to address this, “MASH Cities,” calls on municipalities to integrate MASLD/MASH into local health promotion, food policy, urban mobility, and primary care services to mitigate disease progression.³³ Major cities in Spain should consider joining this growing platform for sharing learned lessons and best practices. Empowering cities with the mandate and resources to act on liver health can serve as a scalable, equitable response to this growing challenge, as was proposed for Barcelona in May 2025.³⁴

Additionally, inclusion of MASLD/MASH in Spain’s Public Health Surveillance Strategy (2022)³⁵ could strengthen early detection and monitoring by enabling systematic data collection and risk assessment in both health and non-health sectors, such as urban planning and food policy. Primary care would be central to this approach, serving as the frontline for MASLD screening, risk stratification, and referral. Integration can help standardise primary care practices, including routine FIB-4 risk stratification of individuals with obesity, T2D, metabolic syndrome, or hepatic steatosis—which are often undetected until advanced stages.³⁶ Primary care should be adequately funded and equipped to screen, stratify, manage cardiometabolic risks, and refer high-risk patients, forming the backbone of MASLD/MASH prevention and control at the national, autonomous community, and city levels.^37,38

Registration fees

Category	Early Bird (before 1 April)	On-site
Private Sector/Industry	495	695
Start-up*	150	200
Healthcare Professional, Academic, Public Health/Professional Association, NGO	100	150
Young Researcher / Trainee / PostDoc / Student / Young Person (under 25) *	50	50
Patient or Patient Representative *	50	50

* Registration fee scholarship offered on application, please email: lisa.rice@isglobal.org

Criteria for start-ups:

Early-stage start-up (e.g., pre-seed, seed, or Series A) / Incorporated for under 5 years

Raised under $5 million in funding / Annual revenue less than $1 million

Fewer than 50 employees

What’s included in your ticket?

Entry to all main agenda sessions starting 2pm on 5 June

5 June: Lunch and afternoon networking coffee, and networking buffet reception

6 June: Morning and afternoon networking coffee, and networking lunch

In-person Flagship Gathering 2027

Save the Date:
2027 Flagship Event

About the event

Programme at a glance

An intentionally different kind of meeting

Hear More from Last Year’s Event

See More from Last Year’s Event

Diagnostic Innovations and Models of Care for Steatotic Liver Disease

Policy Readiness to Confront the Steatotic Liver Disease Public Health Threat

Where MetALD and ARLD Meet in Metabolic Care

The Venue

Become a sponsor

Interested in becoming a sponsor of the event?

Additional inquiries

Would you like to collaborate or partner with us? Do you have any questions?

Feel free to reach out!

Registration fees

All applications for registration will be reviewed, and you will be notified of your invitation status and fee via email within one week.

Criteria for start-ups:

What’s included in your ticket?

5. Strengthen the capacity of community health services to prevent and treat MASLD through social prescribing

5. Leverage electronic health records (EHR) through integrated automated diagnostic tools

4. Increase awareness and education of MASLD/MASH among at-risk groups and healthcare professionals

3. Add MASLD/MASH as an indicator to the list of Key Health System Indicators

2. Create a national MASLD registry, cohort, or observatory

1. Launch a Ministry of Health-led whole-of-government strategy

References

What is ALD?

What is MetALD?

What is MASLD?

What is steatotic liver disease?

Further reading

Registration fees

Criteria for start-ups:

What’s included in your ticket?

Agenda

5 June 2025

6 June 2025

*CARPA

In-person Flagship Gathering 2027

Save the Date: 2027 Flagship Event

About the event

Programme at a glance

An intentionally different kind of meeting

Hear More from Last Year’s Event

See More from Last Year’s Event

The Venue

Become a sponsor

Interested in becoming a sponsor of the event?

Additional inquiries

Would you like to collaborate or partner with us? Do you have any questions?

Feel free to reach out!

Registration fees

All applications for registration will be reviewed, and you will be notified of your invitation status and fee via email within one week.

5. Strengthen the capacity of community health services to prevent and treat MASLD through social prescribing

5. Leverage electronic health records (EHR) through integrated automated diagnostic tools

4. Increase awareness and education of MASLD/MASH among at-risk groups and healthcare professionals

3. Add MASLD/MASH as an indicator to the list of Key Health System Indicators

2. Create a national MASLD registry, cohort, or observatory

1. Launch a Ministry of Health-led whole-of-government strategy

References

What is ALD?

What is MetALD?

What is MASLD?

What is steatotic liver disease?

Further reading

Registration fees

Agenda

*CARPA

Save the Date:
2027 Flagship Event